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Center Patents
Published
1. Title of the Patent: Coriander Extract for Bone Cancer
Application Number: 201931032613A
Name of the Inventor: Preetha Bhadra
2. Title of the Patent: Clove Extract for Ovarian Cancer
Application Number: 201931032614A
Name of the Inventor: Preetha Bhadra
3. Title of the Patent: Methi Extract for Liver Cancer
Application Number: 201931032615A
Name of the Inventor: Preetha Bhadra
4. Title of the Patent: Bramhi Extract for Lung Cancer
Application Number: 20193102616A
Name of the Inventor: Preetha Bhadra
5. Title of the Patent: Harataki extract composition for Jaundice
Application Number: 201931054080A
Name of the Inventor: Preetha Bhadra and Atanu Deb
6. Title of the Patent: Methi Extract Based Biopesticide Composition
Application Number: 202031024946
Name of the Inventor: Preetha Bhadra
7. Title of the Patent: A Bio-Pesticide Composition based on Peppermint Extract and its Preparation Method thereof
Application Number: 202031024943
Name of the Inventor: Preetha Bhadra
8. Title of the Patent: A Biopesticide Composition based on Bael Extract and its Preparation Method
Application Number: 202031024944
Name of the Inventor: Preetha Bhadra
9. Title of the Patent: Cumin Extract Based Biopesticide Composition
Application Number: 202031024945
Name of the Inventor: Preetha Bhadra
10. Title of the Patent: Lemongrass as targeted therapy for Brain Cancer
Application Number: 201931013038
Name of the Inventor: Preetha Bhadra
11. Title of the Patent: A Device for Detection of Food Mycotoxin
Application Number: 201931049814
Name of the Inventor: Preetha Bhadra
Product Development
Product | Stage | Expected Completion Date |
Cleanser | Gel formation done, we will go for testing now | September, 2021 |
Day Cream | Cream formulation done, we will go for testing now | September, 2021 |
Nano Curcumin | First phase Extraction Completed | November, 2021 |
1. Name of the Investigator: Dr. Preetha Bhadra
Funded By: Seed Money Grant
Topic: Biopesticides Using different medicinal Plants
Concept of the Proposal:
Medicinal plants, also called medicinal herbs, have been discovered and used in traditional medicine practices since prehistoric times. Plants synthesise hundreds of chemical compounds for functions including defence against insects, fungi, diseases, and herbivorous mammals. Numerous phytochemicals with potential or established biological activity have been identified. However, since a single plant contains widely diverse phytochemicals, the effects of using a whole plant as medicine are uncertain. Further, the phytochemical content and pharmacological actions, if any, of many plants having medicinal potential remain unassessed by rigorous scientific research to define efficacy and safety.
Objective:
Biopesticides are certain types of pesticides that are derived from natural materials like plants (Botanical origin ), bacteria, fungi and virus (Microbial origin) and certain minerals. When used as a component of Integrated Pest Management (IPM) programs these biopesticides can
greatly decrease the use of conventional pesticides, while crop yields remain high. The BioPesticides control pests / diseases either selectively or with broad-spectrum approach. Biopesticides are usually inherently less toxic than conventional pesticides. Biopesticides are generally target specific and affect only the target pest and closely related organisms vis-à-vis broad spectrum, conventional pesticides that may also affect organisms such as birds, insects and mammals. We want to define this problem with a bio-solution using BIOVIA and some other fieldwork.
2. Name of the Investigator: Dr. Preetha Bhadra
Funded By: Seed Money Grant
Topic: Targeted therapy for different Cancer
Concept of the proposal:
Ancient India is one of the pioneers of studies of plants as medicine, i.e. Ayurveda. In our social and economic life, we hardly take care of the food we are taking. The uses of various pesticides, preservatives, etc. turn the foods into poison. Moreover the side effects of these pesticides and preservatives etc. are dangerous because it leads to the initiation of different cancer. In this whole world, the number of patients dying from cancer is increasing in a very threatening way. We found Medicinal plant is packed with antioxidants that help in detoxing and cleansing from within. The medicinal plant is a source of powerful antioxidants. Phenolic compounds like catechin, alkanols, apigenin, and linalool are found in Coriandrum sativum. These kinds of antioxidants help to scavenge free radicals, which can be very detrimental to the body if not cleared properly. The Medicinal plant is also thought to have potent anticancer abilities against some cancer cell lines. Due in large part to its antioxidant capabilities, the medicinal plant is considered a possible tool to help treat cancer. Extract from the root of the plant has been shown to inhibit DNA damage, prevent cancer cell migration, and promote cancer cell death in laboratory studies. Several components of Medicinal plant help fight cancer. This occurs either by causing cell death directly or boosting your immune system so that your body is better able to fight off cancer on its own. Medicinal plant tea is sometimes used as an adjuvant therapy during chemotherapy and radiation. It helps in removal of toxins from the body by relieving fluid retention. It has to be a potential drug for cancer in the wet lab using different methods like, Fluorescence Spectroscopy, Reactive Oxygen Species (ROS), MTT assay, Circular Dichroism (CD). After getting a good result we further targeted some of the genes responsible for Cancer IL6 (6MG1), VDR (5XZF), MTOR (5YK5) and pharmacophores Decene (6DJC), 2- Bornyl acetate (5ZF4) from Medicinal plant and did some in silico analysis. In this, we have found that these two pharmacophores are having better Mol Doc score from any others. From this, we can deduce that these two pharmacophores can be a solution to Cancer in near future.
Objective:
We have first studied the effect of Medicinal plant extract on Cancer cell line and the observed some significant result in MTT assay, followed by ROS analysis and Fluorescence Anisotropy, from which we have decided to target some genes responsible for Cancer IL6 (6MG1), VDR (5XZF), MTOR (5YK5) and pharmacophores Decene (6DJC), 2- Bornyl acetate (5ZF4) from Medicinal plant. After identification of the genes and pharmacophores, we did the docking and got some positive value. From this analysis report, this can be concluded that some pharmacophores of Medicinal plant have an effect on the Cancer. Some of the animal studies followed by the isolation of the targeted pharmacophore and the effect on the gene (in-vitro and in-vivo analysis) are on process. Based on this the new drug design is also in the long term future work.
Preparation of Herbal Extract:
1) Selection of the plant 2) Collecting the Plant, 3) Preparing the plant extract: It involves steps such as cutting , washing and chopping of the plant and then extraction 4) Keeping it for a period of at least 3-4 weeks before using it 5) Filtration 6) Storage under refrigerated conditions
3. Name of the Investigator: Dr. Chandana Adhikari
Funded By: Seed Money Grant
Topic: Synthesis, characterization, and application of biopolymer stabilized double emulsion system
Concept of Proposal:
The design of effective delivery systems has recently become an integral part of the development of new medicines to tackle the restrictions associated with traditional drug delivery. The low bioavailability, poor stability, bitter taste and unpleasant odour of certain active agents are some of the most common obstacles and needs to be considered while formulating an effective drug delivery system. In this context, encapsulation of drugs plays a vital role in overcoming the aforementioned obstacles and also helpful in preventing the premature degradation of active agents such as protein and peptides. The present research work focus on the development of an IDS (Intelligent delivery system) by encapsulation to protect bioactive molecules from degradation and improve their bioavailability.
Objective:
Preparation of modified double emulsion-based ternary composites in its solid particulate form will be performed by various protocols like evaporation, spray drying and freeze-drying, etc. For the characterization of the modified double emulsion (MDE) system, FESEM, TEM,
AFM will be used to analyse surface morphologies; FTIR, XRD, TGA-DTA to inspect the characteristic peaks of the functional groups and the molecular characterization (amorphous/crystalline); N 2 adsorption-desorption analyser using BET theory to characterize the porous structure and surface area; the rheological study will be carried out to estimate the mechanical strength along with the elasticity, and finally, swelling ratio measurement will predict the water content capacity and the gel characteristics. After structural and morphological characterization of the prepared MDE system, release or delivery of the entrapped bioactive compounds/drug molecules to the stimulated physiological environment will be studied with help of UV-visible spectrophotometer.
4. Name of the Investigator: Dr. Rosy Malik
Funded By: Seed Money Grant
Topic: Development of cellulose nanocrystal (CNC) supported heterogeneous organocatalysts and study of their recyclability: A step forward towards ‘green’ synthesis
Concept of the proposal
Strategies to synthesize heterogeneous organocatalysts have gained importance recently due to their advantages, such as the ready separation of products and the reusability of catalysts, which are very important in large-scale production. Inorganic and polymeric supports have been used for immobilization of the catalysts in most cases. On the other hand, the emphasis on environmentally friendly and sustainable resources and processes is leading to the increasing use of natural materials in catalysis. Biopolymers, such as cellulose and chitosan represent a diverse and versatile class of materials that are cheap and widely abundant in nature. Hence, these materials have attracted great interest as supports for catalysts in recent years. In this context, cellulose in its various forms can be used as a resource for chiral induction.
Objective:
The objective of the proposed work is to synthesize heterogeneous organocatalysts using cellulose as support and study their reactivity and selectivity towards asymmetric reactions. As amino acids are versatile catalysts for covalent organocatalysis and catalyze a plethora of organic transformation through enamine and iminium catalytic cycles, cellulose-supported catalysts derived from a range of amino acids will be studied within this project.
1. Name of the Investigator: Mr. M. Vijay & Shashikant Tewary (2015-2016)
Sponsored By: Nutraceutical, Food & Flavour Industries
Topic: Phyto Chemical Research & Extraction
2. Name of the Investigator: Shashikant Tewary (2016-2017)
Sponsored By: Nutraceutical, Food & Flavour Industries
Topic: Phyto Chemical Research & Extraction
3. Name of the Investigator: Dr. G. V. Ramana (2016-2017)
Sponsored By: Nutraceutical, Food & Flavour Industries
Topic: Phyto Chemical Research & Extraction
4. Name of the Investigator: Dr. G. V. Ramana (2017-2018)
Sponsored By: Nutraceutical, Food & Flavour Industries
Topic: Phyto Chemical Research & Extraction
5. Name of the Investigator: Dr. G. V. Ramana (2018-2019)
Sponsored By: Nutraceutical, Food & Flavour Industries
Topic: Phyto Chemical Research & Extraction
6. Name of the Investigator: Dr. G. V. Ramana (2019-2020)
Sponsored By: Nutraceutical, Food & Flavour Industries
Topic: Phyto Chemical Research & Extraction
7. Name of the Investigator: Dr. Preetha Bhadra, Dr. Pradipta Banerjee, Dr. Rosy Mallik (2021-2022)
Sponsored By: Spice Board
Topic: Affordable and efficacious skincare products based on natural spice extracts obtained from super critical CO2 extraction process
1.ITC
2. Nutrify India
3. Gram Tarang Foods
http://courseware.cutm.ac.in/courses/domain-nutraceuticals/
2. Commodity and Food Storage
http://courseware.cutm.ac.in/courses/commodity-and-food-storage/
3. Food Processing
http://courseware.cutm.ac.in/courses/food-processing/
4. Dairy Processing and Development
http://courseware.cutm.ac.in/courses/dairy-processing-and-development/
Lab Equipment
Accepted:
Accepted:
2021:
1. Bhadra P, Mukherjee S., 2021. MgO and MgO@SiO2: A Noble Therapeutic Drug for Cancer and Microbial Contamination. JMBFS (Scopus).
2. Bhadra P, Mukherjee S., 2021. Comparative Study of the Changes of Proteins in Different Blood Component with respect to the Detection with Optical Nano Fiber. JMBFS (Scopus).
3. Adhikary K, Chatterjee A, Banerjee P., 2021. Nanomaterials for Biomedical Advancements: Concepts and Applications. Bioscience Biotechnology Research Communications (WoS).
4. Madumita M, Behera G, Nanda A, Das PK, Pradhan S and Sarkar A., 2021. Effect of hot air, microwave and freeze drying on drying characteristics of button mushroom slices (Agaricus Bisporus). Journal of Scientific Research and Reports (NAAS).
Webinars Organized
I am playing the role of an Assistant Professor, Department of Biotechnology, Centurion University of Technology and Management, Parlakhemundi, and also Coordinator of Centre for Phytopharma. I have completed my PhD in Biophysics and worked on mostly Cancer cells, Stem cell biology, and molecular biology. I am current;y working on the effect of different medicinal […]
Analytical Instruments Handled: Laser Capture Microdissection (LCM, Carl Zeiss), Cryostat, HPLC, FT-IR, Rotary Evaporator, UV-Vis Spectrophotometer, Light Microscope, Fluorescent Microscope, Confocal Microscope (LSM880, Carl Zeiss), Axioscanner (Carl Zeiss), Cytospin, Soxhlet Apparatus, Distillation set Practical Exposures Molecular Biology Techniques: Real time-PCR, ELISA, Plasmid isolation, Histological staining (Immunocytochemistry, Immunohistochemistry), RNA isolation using various kits, c-DNA synthesis using […]
having 16 years of teaching experience. Completed Ph.D. in 2018 from Sambalpur University. The title of my thesis was “Correlational Analysis in Chemical Processes using Empirical and Topological Parameters.”
Completed B. Tech (2008-2012) in Agricultural Engineering from CAET, OUAT. Qualified M. Tech (2012-2014) from the same university with specialization in Food Process Engineering. I completed my Ph.D. Degree from the National Institute of Technology in Food Process Engineering. My aim is to pursue a challenging career and contemplate working in an academic institution with […]
Dean Academics, M.S.Swaminathan School of Agriculture
Soma Maji is working as an Assistant Professor in the Department of Dairy Technology, School of Agriculture and Bio Engineering, Centurion University of Technology and Management, Paralakhemundi, Odisha. She is B.Tech in Dairy Technology, M.Tech in Dairy Chemistry from WBUAFS, West Bengal Nadia and pursuing PhD in Dairy Chemistry from NDRI, Karnal. She has qualified ARSB NET in Dairy […]
Dr. Rajashree Jena is currently working as an Assistant Professor in the Department of Dairy Technology, Centurion University of Technology and Management, Paralakhemundi Campus, Odisha. She has obtained her Ph. D degree from National Dairy Research Institute, Karnal in the field of Dairy Microbiology. She has more than 3 years of research and teaching experience […]
Availing the opportunity to put my best skill in the field that will give me a benchmark position to my organization among the competitor with available resources within time.
To secure a position with a stable and profitable organization, where I can be a member of a team and utilize my educational experience to the fullest. Seeking a challenging position in a well-established company that offers professional growth and opportunity to learn and enrich my competencies in my profession.
Sujit Kumar Mishra is working as Assistant Professor in the School of Applied Sciences, Centurion University of Technology and Management, Bolangir Campus, Odisha, India. He has completed his M. Sc. from School of Life Sciences, Sambalpur University, submitted his Ph. D. thesis in Sambalpur University, and awaiting award of the doctoral degree. He has awarded […]